2025年4月28日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就由副地衣芽孢杆菌DSM 33902和枯草芽孢杆菌DSM 33903组成的饲料添加剂对奶牛和其他反刍动物的安全性和有效性发表科学意见。
经过评估，专家小组认为在建议的使用条件下该添加剂对目标物种、消费者和环境是安全的。部分原文报道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Bovacillus™, a product containing viable cells of Bacillus paralicheniformis DSM 33902 and Bacillus subtilis DSM 33903, which is intended to be used as a zootechnical additive (functional group: gut flora stabiliser) in the feed of dairy cows and other dairy ruminants. The trade name is Bovacillus™, and it is intended to be commercialised in two formulations: Bovacillus™ 10, to use in feed, and WS, to use in drinking water. B. paralicheniformis and B. subtilis are considered suitable for the qualified presumption of safety (QPS) approach to safety assessment. The identity of the active agents was established, and compliance with the applicable qualifications /confirm/ied. Therefore, Bacillus paralicheniformis DSM 33902 and Bacillus subtilis DSM 33903 are presumed safe for the target species, consumers of products derived from animals fed the additive and the environment. Since no concerns are expected from the other components of the additive, Bovacillus™ is also considered safe for the target species, consumers and the environment. Bovacillus™ 10 and WS are not skin or eye irritants. Due to the nature of the active agents, both forms of the additive are considered respiratory and skin sensitisers. The Panel concludes that Bovacillus™ has the potential to be efficacious as a zootechnical additive when supplemented in the feed of dairy ruminants at 3.8 × 108 CFU/kg complete feed.
