2025年10月17日，欧盟食品安全局就一种磷脂酶D（phospholipase D）的安全性评价发布意见。
据了解，这种食品酶是由非转基因纺锤链霉菌菌株DSM 40093生产的，旨在用于从卵磷脂生产改性磷脂。
经过评估，专家小组认为，在预期的使用条件下，不能排除饮食暴露引起过敏反应的风险，但这种情况发生的可能性很低。根据所提供的数据，评估小组得出结论，这种食品酶在预期使用条件下不会引起安全问题。部分原文报道如下：
The food enzyme phospholipase D (phosphatidylcholine phosphatidohydrolase; EC 3.1.4.4) is produced with the non-genetically modified microorganism Streptomyces netropsis strain DSM 40093 by Chemi S.p.A. The food enzyme was considered free from viable cells of the production organism. The food enzyme is intended to be used in the production of modified phospholipids from lecithin. Since residual amounts of total organic solids of the food enzyme are removed by repeated washing steps, dietary exposure was not calculated and the toxicity testing was considered unnecessary. A search for the homology of the amino acid sequence of the phospholipase D to known allergens was made and no match was found. The Panel considered that a risk of allergic reactions upon dietary exposure to the food enzyme cannot be excluded but that the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
