2026年5月22日，据欧盟食品安全局（EFSA）消息，应欧盟委员会要求，欧盟动物饲料添加剂和产品（FEEDAP）研究小组就谷氨酸棒杆菌CCTCC M 20232578发酵生产的L-缬氨酸（L‐valine）作为所有动物饲料添加剂的安全性和有效性发表科学意见。
经过评估，专家小组认为该添加剂对目标物种、消费者和环境是安全的。评估中的添加剂被认为是所有非反刍动物物种氨基酸L-缬氨酸的有效来源。为了使补充的L-缬氨酸对反刍动物和非反刍动物同样有效，需要防止其在瘤胃中降解。部分原文报道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-valine produced with a non-genetically modified strain of Corynebacterium glutamicum (CCTCC M 20232578) as a nutritional feed additive, to be used in feed or water for drinking for all animal species and categories. The production strain meets the qualifications for the qualified presumption of safety (QPS) approach to safety assessment and is considered safe. The use of l-valine produced with C. glutamicum CCTCC M 20232578 in feed was considered safe for the target species when supplemented in appropriate amounts to the diet according to the nutritional needs of the species. The FEEDAP Panel had concerns about the use of l-valine in water for drinking. The use of l-valine produced by fermentation with C. glutamicum CCTCC M 20232578 in animal nutrition was considered safe for the consumers of products from animals receiving the additive and to the environment. The FEEDAP Panel could not conclude on the potential of the additive to be irritant to skin and/or eyes and to be a potential skin sensitiser. The additive was regarded as an effective source of the amino acid l-valine for all non-ruminant species. To be as efficacious in ruminants as in non-ruminants, it should be protected from ruminal degradation.
