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欧盟评估转基因枯草芽孢杆菌菌株DP-Eyp97生产的葡聚糖蔗糖酶的安全性

   2026-06-25 食品伙伴网泽夕665
核心提示:2026年6月24日,欧盟食品安全局就一种葡聚糖蔗糖酶(dextransucrase)的安全性评价发布意见。……(世界食品网-www.shijieshipin.com)
     2026年6月24日,欧盟食品安全局就一种葡聚糖蔗糖酶(dextransucrase)的安全性评价发布意见。 
  据了解,这种食品酶是由转基因枯草芽孢杆菌菌株DP-Eyp97生产的,旨在用于糖的加工,以生产低聚糖和多糖。
 
  经过评估,专家小组认为,在预期的使用条件下,不能排除饮食暴露引起过敏反应的风险,但这种情况发生的可能性很低。因为没有证据表明食品酶中不存在来自生产生物体的DNA,所以专家组无法对食品酶的安全性做出结论。部分原文报道如下:
 
  The food enzyme dextransucrase (sucrose:1,6-α-d-glucan 6-α-d-glucosyltransferase; EC 2.4.1.5) is produced with the genetically modified Bacillus subtilis strain DP-Eyp97 by Genencor International B.V. The production strain met the requirements for the qualified presumption of safety. The food enzyme was considered free from viable cells of the production organism and its DNA. The food enzyme is intended to be used in the processing of sugars for the production of oligo- and polysaccharides in situ. Dietary exposure was estimated to be up to 27.598 mg total organic solids/kg body weight per day in European populations. Given the QPS status of the production strain and the absence of concerns resulting from the food enzyme manufacturing process, toxicity tests were considered unnecessary by the Panel. A search for the homology of the amino acid sequence of the dextransucrase to known allergens was made, and no match was found. The Panel considered that a risk of allergic reactions upon dietary exposure to the food enzyme cannot be excluded, but that the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use.
 
 
地区: 欧盟
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