2025年4月24日，欧盟食品安全局就一种食品酶内切-1,3（4）-β-葡聚糖酶（endo-1,3(4)-β-glucanase）的安全性评价发布意见。
据了解，这种食品酶是由非转基因Cellulosimicrobium funkei菌株AE-TN生产的。
经过评估，专家小组认为，该食品酶在预期的使用条件下不会引起安全问题。部分原文报道如下：
The food enzyme endo-1,3(4)-β-glucanase (3-(1–3;1–4)-β-D-glucan 3(4)-glucano‑hydrolase; EC 3.2.1.6) is produced with the non-genetically modified (GM) Cellulosimicrobium funkei strain AE-TN by Amano Enzyme Inc. The production organism belongs to a species implicated in opportunistic infections in humans. In a previous evaluation, the Panel did not consider the food enzyme safe due to the presence of viable cells of the production strain in the food enzyme. As a follow-up, the applicant improved the quality assurance system by introducing a pressure check of the microfiltration step of the food enzyme manufacturing process and the production strain was no longer detected in new food enzyme batches. The Panel accepted the results. based on the new data and the previous evaluation, the Panel concluded that the food enzyme endo-1,3(4)-β-glucanase produced with the non-GM C. funkei strain AE-TN does not give rise to safety concerns under the intended conditions of use.
